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ChemicalBook CAS DataBase List Iodobenzene
591-50-4

Iodobenzene synthesis

9synthesis methods
-

Yield:591-50-4 90%

Reaction Conditions:

with iodine in acetonitrile at 120; for 0.0833333 h;Microwave irradiation;chemoselective reaction;

Steps:

4. 2. Typical Procedure for Iodinationof Alcohol
General procedure: To a suspension of polymer-bound triphenylphosphine (1.2 mmol) in anhydrous acetonitrile (10 mL) were added iodine (1 mmol) and 1,6-hexanediol diol (1mmol). The reaction mixture was irradiated in microwave reactor at 120 °C for 3 min. The reaction mixture was filtered over a filter paper and washed with chloroform.The filtrate was extracted with aqueous sodium thiosulfate solution and dried with anhydrous sodium sulfate.The reafter, solvent was removed under reduced pressure to obtain 6-iodohexan-1-ol (30) in 93%

References:

Das, Diparjun;Chanda, Tridib;Rokhum, Lalthazuala [Acta Chimica Slovenica,2015,vol. 62,# 4,p. 775 - 783]

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