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124012-42-6

Galocitabine synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: pyridine / CH2Cl2 / -20 - 20 °C
2: NaOH / methanol; H2O / -20 - -5 °C

References:

Shimma, Nobuo;Umeda, Isao;Arasaki, Motohiro;Murasaki, Chikako;Masubuchi, Kazunao;Kohchi, Yasunori;Miwa, Masanori;Ura, Masako;Sawada, Noriaki;Tahara, Hitoshi;Kuruma, Isamu;Horii, Ikuo;Ishitsuka, Hideo [Bioorganic and Medicinal Chemistry,2000,vol. 8,# 7,p. 1697 - 1706]

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