Fmoc-β-HomoTrp(Boc)-OH synthesis
- Product Name:Fmoc-β-HomoTrp(Boc)-OH
- CAS Number:357271-55-7
- Molecular formula:C32H32N2O6
- Molecular Weight:540.61
143824-78-6
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Yield:-
Steps:
Multi-step reaction with 2 steps
1.1: Et3N; i-BuOCOCl / tetrahydrofuran / 0.25 h / -25 °C
1.2: 50 percent / tetrahydrofuran; diethyl ether / 0 - 20 °C
2.1: 71 percent / CF3COOAg; NMM / tetrahydrofuran; H2O / 8 h / 0 - 20 °C
References:
Gademann;Kimmerlin;Hoyer;Seebach [Journal of Medicinal Chemistry,2001,vol. 44,# 15,p. 2460 - 2468]
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