ChemicalBook CAS DataBase List ETHYL (4-BROMOANILINO)(OXO)ACETATE

ETHYL (4-BROMOANILINO)(OXO)ACETATE synthesis

6synthesis methods

Product Name:ETHYL (4-BROMOANILINO)(OXO)ACETATE
CAS Number:24451-15-8
Molecular formula:C10H10BrNO3
Molecular Weight:272.1

4755-77-5 Synthesis

4755-77-5
341 suppliers
$9.00/25g

106-40-1 Synthesis

106-40-1
474 suppliers
$12.00/5g

24451-15-8
29 suppliers
$25.00/100mg

Yield:24451-15-8 95%

Reaction Conditions:

with triethylamine in tetrahydrofuran at 20; for 0.5 h;Inert atmosphere;

Steps:

3

General procedure: The ethyl ester derivatives of the N-2,4,6-trimethylphenyloxamate(2,4,6-Me3pma), N-4-bromophenyloxamate (4-Brpma) and N-4-chlorophenyloxamate (4-Clpma) ligands were prepared by followinga previously reported procedure (Scheme 2) [33,34]. Thecorresponding aniline derivative (83 mmol) was dissolved in THF(250 mL) under dinitrogen and the resulting solution was treatedwith ethyl chlorooxoacetate (9.3 mL, 83 mmol) in presence of triethylamine(12 ml, 83 mmol) at room temperature under continuousstirring for 30 min. The resulting solution was filtered and thesolvent was removed under vacuum to afford an oily crude, whichquickly became solid. The obtained white solid was suspended inwater and filtered off, then washed with a small amount of diethylether and dried under vacuum.

References:

Fortea-Pérez, Francisco Ramón;Neve, Francesco;Armentano, Donatella;De Munno, Giovanni;Stiriba, Salah-Eddine;Julve, Miguel [Inorganica Chimica Acta,2016,vol. 443,p. 267 - 273]

95-92-1 Synthesis