Dodecanamide synthesis
- Product Name:Dodecanamide
- CAS Number:1120-16-7
- Molecular formula:C12H25NO
- Molecular Weight:199.33
2437-25-4
191 suppliers
$28.00/25mL
1120-16-7
109 suppliers
$22.00/5g
Yield:1120-16-7 90%
Reaction Conditions:
with Acetaldehyde oxime;copper(II) chloride dihydrate in water for 12 h;Reflux;
Steps:
Experimental Procedures for Hydration of Various Nitriles
General procedure: To a 25 mL round-bottom flask equipped with magnetic stirrer were added nitrile (2.5 mmol), acetaldoxime (3.75 mmol), copper oxide (0.25 mmol) and H2O (10 mL). The mixture was heated to reflux for 2-14 h. After cooling to room temperature, the solution was directly evaporated to dryness and the residue was purified by column chromatography on silica gel (ethyl acetate/n-hexane) to give the corresponding amides. The commercially available amides were characterised by melting points, 2-amino-5-bromobenzamide (Table 2, entry 6) and 3,4-dichloropicolinamide (Table 2, entry 13) were characterised by NMR spectra and LC-MS.
References:
Ma, Xiao-Yun;He, Ying;Hu, Yu-Lin;Lu, Ming [Tetrahedron Letters,2012,vol. 53,# 4,p. 449 - 452] Location in patent:supporting information; experimental part
106-33-2
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$7.00/25g
1120-16-7
109 suppliers
$22.00/5g
2437-25-4
191 suppliers
$28.00/25mL
143-07-7
744 suppliers
$5.00/25g
1120-16-7
109 suppliers
$22.00/5g
2437-25-4
191 suppliers
$28.00/25mL
10233-13-3
182 suppliers
$5.00/1g
1120-16-7
109 suppliers
$22.00/5g
2437-25-4
191 suppliers
$28.00/25mL
143-07-7
744 suppliers
$5.00/25g
1120-16-7
109 suppliers
$22.00/5g