Docetaxel Impurity 15 synthesis

5synthesis methods

Product Name:Docetaxel Impurity 15
CAS Number:146924-91-6
Molecular formula:C16H15NO3
Molecular Weight:269.3

2,3-Azetidinedione, 1-(4-methoxyphenyl)-4-phenyl-, (4R)-

205518-66-7
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146924-91-6
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Yield:146924-91-6 90%

Reaction Conditions:

with sodium tetrahydroborate in methanol at 0;stereoselective reaction;

References:

Chincholkar, Pinak M.;Kale, Ajaykumar S.;Gumaste, Vikas K.;Deshmukh, Abdul Rakeeb A.S. [Tetrahedron,2009,vol. 65,# 12,p. 2605 - 2609] Location in patent:experimental part

2-Azetidinone, 3-[[(1S,3R,4R,6R)-4-bromo-3,7,7-trimethylbicyclo[4.1.0]hept-3-yl]oxy]-1-(4-methoxyphenyl)-4-phenyl-, (3S,4R)-

283177-09-3
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146924-91-6
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References

186613-02-5 Synthesis

3-(4-METHOXYPHENYL)-2-OXO-4-PHENYLCYCLOBUTYL ACETATE

186613-02-5
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146924-91-6
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146924-90-5
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References

783-08-4
30 suppliers
$61.00/250mg

146924-91-6
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References

104-94-9 Synthesis

104-94-9
487 suppliers
$9.00/1g

146924-91-6
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References

Docetaxel Impurity 15 Related Search:

(2S,3S)-methyl 3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropanoate HLCSYHHJEMPKSY-RRKHLBDSSA-N Paclitaxel 10-Deacetylbaccatin III Docetaxel Impurity 17 ANISOIN Methyl (2R,3S)-3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropionate (3R,4S)-3-Hydroxy-1-(4-methoxyphenyl)-4-phenyl-2-azetidinone