D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid synthesis
- Product Name:D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
- CAS Number:103733-65-9
- Molecular formula:C10H11NO2
- Molecular Weight:177.2
81477-94-3
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91-13-4
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$14.00/1g
103733-65-9
252 suppliers
$5.00/100mg
Yield:103733-65-9 82%
Reaction Conditions:
Stage #1: N-(diphenylmethylene)glycine tert-butyl ester;α,α'-dibromo-o-xylenewith (S,S)-3,4,5-F3-Ph-NAS-Br in potassium hydroxide;toluene at 0; for 6 h;
Stage #2: with hydrogenchloride in tetrahydrofuran;
Stage #3: with sodium hydrogencarbonate
References:
Ooi;Takeuchi;Maruoka [Synthesis,2001,# 11,p. 1716 - 1718]
103733-65-9
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$5.00/100mg
115-11-7
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$45.00/25g
103733-65-9
252 suppliers
$5.00/100mg