ChemicalBook CAS DataBase List Bromobenzene-d5

Bromobenzene-d5 synthesis

5synthesis methods

Product Name:Bromobenzene-d5
CAS Number:4165-57-5
Molecular formula:C6BrD5
Molecular Weight:162.04

108-86-1 Synthesis

108-86-1
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4165-57-5
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$56.29/2g

Yield:4165-57-5 86%

Reaction Conditions:

with 10 % platinum on carbon;water-d2 in isopropanol;cyclohexyl alcohol at 90; for 24 h;Inert atmosphere;

Steps:

11 Example 11

In a 50mL three-necked flask equipped with a condenser tube, a thermometer and electromagnetic stirring, 0.25mmol (39.252mg) of bromobenzene, 5mL of deuterium water, 24.38mg of 10% platinum on carbon, 0.1mL of isopropanol and 0.9mL of cyclohexane solution were added. Argon gas was used to replace the air in the reaction system, then the temperature was raised to 90° C., and the reaction temperature was lowered to room temperature after 24 h, and the catalyst platinum carbon was removed by filtration to obtain a mixture of deuterium water and crude product.10 mL of dichloromethane was added to the mixture, the organic layer and the deuterium water layer were separated, the lower organic layer liquid was collected, and the organic layer liquid was rotary-evaporated at 38°C to obtain 33.757 mg of the product deuterated chlorobenzene liquid with a yield of 86%.

References:

CN113979822,2022,A Location in patent:Paragraph 0050-0052

1076-43-3 Synthesis