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ChemicalBook CAS DataBase List BIS(3,5-DIMETHYLPHENYL)PHOSPHINE
71360-06-0

BIS(3,5-DIMETHYLPHENYL)PHOSPHINE synthesis

4synthesis methods
-

Yield:71360-06-0 92%

Reaction Conditions:

with sodium bis(2-methoxyethoxy)aluminium dihydride in toluene at -5 - 5; for 5.5 h;Inert atmosphere;Reagent/catalyst;Solvent;Temperature;

Steps:

1-3 Example 1
bis(3,5-dimethylphenyl) phosphine oxide (0.88g, 3mmol) stir with toluene (2.5mL) to dissolve. Under the protection of argon, red aluminum toluene solution (70%) (0.87g, 3mmol) and toluene (7.5mL) were added dropwiseThe temperature is controlled at -5-0°C, 0.5h is added dropwise, and -5-5°C is reacted for 5h. After the reaction,Add water to quench at a temperature of <5 , let stand for layering, (stand still at -5 for 20min).Toluene layer is desolvated at 0 110 under reduced pressure, pressure is -0.10MPa,The product bis (3,5-dimethylphenyl) phosphine is obtained.The GC purity of the product was 97%, and the yield was 92%.

References:

Beijing Yingtaijiahe Biological Technology Co., Ltd.;Liu Kaiyang;Zhao Jianmin;Chen Xiaoyu;Yang Hongye;Sun Yanwei CN110950908, 2020, A Location in patent:Paragraph 0022-0031

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