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ChemicalBook CAS DataBase List AMINO-CYCLOHEXYL-ACETIC ACID
5664-29-9

AMINO-CYCLOHEXYL-ACETIC ACID synthesis

12synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 5 steps
1: 85 percent / NaH / tetrahydrofuran
2: sodium azide, ceric ammonium nitrate / acetonitrile / -15 - -5 °C
3: acetic acid / 1 h / 100 °C
4: potassium carbonate, water / methanol
5: 86 percent / H2 / Pd-C

References:

Clive, Derrick L. J.;Etkin, Nola [Tetrahedron Letters,1994,vol. 35,# 16,p. 2459 - 2462]

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