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ChemicalBook CAS DataBase List 2,3-(4-CARBOXYBENZO)-1,4,7,10,13,16-HEXAOXACYCLOOCTADEC-2-ENE
60835-75-8

2,3-(4-CARBOXYBENZO)-1,4,7,10,13,16-HEXAOXACYCLOOCTADEC-2-ENE synthesis

1synthesis methods
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Yield:60835-75-8 70%

Reaction Conditions:

Stage #1:2,3,5,6,8,9,11,12,14,15-decahydro-1,4,7,10,13,16-benzohexaoxacyclooctadecin;trifluoroacetic acid with hexamethylenetetramine for 24.3333 h;Reflux;Inert atmosphere;Cooling with ice;
Stage #2: with hydrogenchloride for 2.5 h;Inert atmosphere;Cooling with ice;

References:

Shao, Shuai;Thomas, Michael B.;Park, Kyu Hyung;Mahaffey, Zoe;Kim, Dongho;D'Souza, Francis [Chemical Communications,2017,vol. 54,# 1,p. 54 - 57] Location in patent:supporting information

FullText

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