ChemicalBook CAS DataBase List 6-Isopropylpyridin-3-ol

6-Isopropylpyridin-3-ol synthesis

5synthesis methods

Product Name:6-Isopropylpyridin-3-ol
CAS Number:101870-78-4
Molecular formula:C8H11NO
Molecular Weight:137.18

55717-45-8 Synthesis

55717-45-8
286 suppliers
$5.00/250mg

101870-78-4
43 suppliers
inquiry

Yield:-

Steps:

Multi-step reaction with 3 steps
1: di-isopropyl azodicarboxylate; triphenylphosphine / dichloromethane / 48 h / 20 °C / Inert atmosphere
2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / 1,4-dioxane / 90 °C / Inert atmosphere
3: 10 wt% Pd(OH)2 on carbon; hydrogen / ethanol / 20 °C

References:

Westaway, Susan M.;Preston, Alex G. S.;Barker, Michael D.;Brown, Fiona;Brown, Jack A.;Campbell, Matthew;Chung, Chun-Wa;Drewes, Gerard;Eagle, Robert;Garton, Neil;Gordon, Laurie;Haslam, Carl;Hayhow, Thomas G.;Humphreys, Philip G.;Joberty, Gerard;Katso, Roy;Kruidenier, Laurens;Leveridge, Melanie;Pemberton, Michelle;Rioja, Inma;Seal, Gail A.;Shipley, Tracy;Singh, Onkar;Suckling, Colin J.;Taylor, Joanna;Thomas, Pamela;Wilson, David M.;Lee, Kevin;Prinjha, Rab K. [Journal of Medicinal Chemistry,2016,vol. 59,# 4,p. 1370 - 1387]