TERT-BUTYL 4-HYDROXY-2-OXOPYRROLIDINE-1-CARBOXYLATE synthesis
- Product Name:TERT-BUTYL 4-HYDROXY-2-OXOPYRROLIDINE-1-CARBOXYLATE
- CAS Number:409341-03-3
- Molecular formula:C9H15NO4
- Molecular Weight:201.22
924-49-2
123 suppliers
$18.00/5g
24424-99-5
840 suppliers
$13.50/25G
999-97-3
645 suppliers
$9.00/5G
409341-03-3
36 suppliers
$45.00/50mg
Yield:409341-03-3 89%
Reaction Conditions:
Stage #1: DL-4-amino-3-hydroxybutyric acid;1,1,1,3,3,3-hexamethyl-disilazanewith pyridine in 5,5-dimethyl-1,3-cyclohexadiene at 118; for 14 h;Large scale;
Stage #2: di-tert-butyl dicarbonatewith dmap in Isopropyl acetate at 10 - 20; for 17.5 h;Large scale;
Stage #3: with triethylamine tris(hydrogen fluoride) in Isopropyl acetate; for 1 h;Large scale;
References:
Tian, Zhenping;Rasmussen, Michael;Wittenberger, Steven J. [Organic Process Research and Development,2002,vol. 6,# 4,p. 416 - 418]
924-49-2
123 suppliers
$18.00/5g
24424-99-5
840 suppliers
$13.50/25G
73602-61-6
340 suppliers
$11.00/10g
409341-03-3
36 suppliers
$45.00/50mg