ChemicalBook CAS DataBase List 4-Pyridylcarbinol

4-Pyridylcarbinol synthesis

12synthesis methods

Product Name:4-Pyridylcarbinol
CAS Number:586-95-8
Molecular formula:C6H7NO
Molecular Weight:109.13

1570-45-2 Synthesis

1570-45-2
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586-95-8
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$6.00/1g

Yield:586-95-8 74.5%

Reaction Conditions:

with hydrogen;[2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine];tris(2,4-pentanedionato)ruthenium(III) in isopropyl alcohol at 150; under 112511 Torr; for 24 h;Product distribution / selectivity;

Steps:

1; 2; 3
In an autoclave, the reactant and Ru(acac)₃were dissolved with 1.4 equivalents of tris(diphenylphosphinomethyl)ethane in isopropanol, and converted at 150° C. and 150 bar of hydrogen pressure for 24 h. After the reaction, the reaction mixture was analyzed by gas chromatography.Conversion, selectivity and yield were determined by means of gas chromatography. Substrates, batch sizes and analysis are compiled in Table 1.

References:

BASF SE US2009/43102, 2009, A1 Location in patent:Page/Page column 1-2

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872-85-5 Synthesis