4-ISOXAZOLEBORONIC ACID PINACOL ESTER synthesis
- Product Name:4-ISOXAZOLEBORONIC ACID PINACOL ESTER
- CAS Number:928664-98-6
- Molecular formula:C9H14BNO3
- Molecular Weight:195.02
847490-69-1
77 suppliers
$38.00/250mg
61676-62-8
314 suppliers
$10.00/5g
928664-98-6
116 suppliers
$14.00/100mg
Yield:928664-98-6 90%
Reaction Conditions:
Stage #1:4-iodoisoxazole with TurboGrignard in tetrahydrofuran at -78; for 0.5 h;Inert atmosphere;
Stage #2:2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in tetrahydrofuran at 0; for 4.5 h;Inert atmosphere;
References:
Morita, Taiki;Fuse, Shinichiro;Nakamura, Hiroyuki [Angewandte Chemie - International Edition,2016,vol. 55,# 43,p. 13580 - 13584][Angew. Chem.,2016,vol. 128,p. 13778 - 13782,5] Location in patent:supporting information