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ChemicalBook CAS DataBase List 4-Fluorobenzenesulfonyl chloride
349-88-2

4-Fluorobenzenesulfonyl chloride synthesis

10synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: bis(tricyclohexylphosphine)nickel(II) dichloride; 2-picoline borane complex / 1-methyl-pyrrolidin-2-one / 18 h / 60 °C / Schlenk technique; Inert atmosphere; Sealed tube
2: 1-methyl-pyrrolidin-2-one; water / 1 h / 4 °C / Inert atmosphere; Schlenk technique
3: N-chloro-succinimide; hydrogenchloride / acetonitrile; water / 15 h

References:

Magné, Valentin;Ball, Liam T. [Chemistry - A European Journal,2019,vol. 25,# 37,p. 8903 - 8910]

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