成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 4-CHLORO-2,6-DIMETHYLPYRIMIDINE
4472-45-1

4-CHLORO-2,6-DIMETHYLPYRIMIDINE synthesis

8synthesis methods
-

Yield: 82%

Reaction Conditions:

with trichlorophosphate in toluene for 3 h;Reflux;

Steps:

1.1.7. Preparation of 4-chloro-2,6-dimethylpyrimidine
POCl3 (0.460 g, 3.0 mmol) was added to the solution of compound 13 (1.0 mmol) in 15 mL of toluene and the mixture was stirred at reflux for 3 hours. Redundant POCl3 was removed under reduced pressure and ice water (10mL) was added. The solution was adjusted to the pH 9-10 with sodium carbonate and then extracted with methyl tert-butyl ether (MTBE). The organic phase was dried over sodium sulfate, and the solvent was removed under reduced pressure to afford compound 14. (Yield: 82%) MS (ESI) (m /z) [M+H]+ 143.1.

References:

Xu, Shaoyu;An, Baijiao;Li, Yuxin;Luo, Xunbang;Li, Xingshu;Jia, Xian [Bioorganic and Medicinal Chemistry Letters,2018,vol. 28,# 10,p. 1769 - 1775] Location in patent:supporting information

4-CHLORO-2,6-DIMETHYLPYRIMIDINE Related Search: