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ChemicalBook CAS DataBase List 4-Amino-3,5-dichlorophenacylbromide
37148-47-3

4-Amino-3,5-dichlorophenacylbromide synthesis

3synthesis methods
Dissolve 4-amino-3, 5-dichloroacetophenone in chloroform and heat to 65°C. Add bromine dropwise with stirring, stir for a few minutes after adding, then add ethanol and stir. Freeze, filter out the crystals, wash with chloroform, and dry at low temperature to obtain finished products.
37148-48-4 Synthesis
4-Amino-3,5-dichloroacetophenone

37148-48-4
370 suppliers
$6.00/1g

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Yield:37148-47-3 95.2%

Reaction Conditions:

with bromine at 20; for 3 h;

Steps:

2.2 Preparation of 3,5-dichloro-4-amino-α-bromoacetophenone

In a 100 mL three-necked flask, 5.1 g of 3,5-dichloro-4-aminoacetophenone,Add 20mL chloroform,Bromine was added dropwise 10g,After adding at room temperature for 3 hours,Stop the reaction,neutralize,The solvent was recovered after washing to give 6.7 g of a light yellow solid,Yield 95.2%,HPLC detection,Purity 99.0%.

References:

CN105968021,2016,A Location in patent:Paragraph 0170-0171

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