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39604-64-3

1-(2-Hydroxy-4-methoxyphenyl)-2-(4-methoxyphenyl)ethanone synthesis

13synthesis methods
Preparation by partial methylation of 2,4-di-hydroxyphenyl 4-methoxybenzyl ketone,
? with methyl iodide in the presence of potassium carbonate in boiling acetone during 3 h (83%);
? with dimethyl sulfate, in the presence of potassium carbonate in boiling acetone ;
? with diazomethane in ethyl ether.
-

Yield:39604-64-3 94%

Reaction Conditions:

with cerium(III) chloride;sodium iodide in acetonitrile; for 43 h;Heating;

References:

Kamada, Atsushi;Sasaki, Atsushi;Kitazawa, Noritaka;Okabe, Tadashi;Nara, Kazumasa;Hamaoka, Shinichi;Araki, Shin;Hagiwara, Hiroaki [Chemical and Pharmaceutical Bulletin,2004,vol. 52,# 1,p. 79 - 88]

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