3-FLUORO-2-TRIFLUOROMETHYL-ISONICOTINIC ACID synthesis
- Product Name:3-FLUORO-2-TRIFLUOROMETHYL-ISONICOTINIC ACID
- CAS Number:886510-09-4
- Molecular formula:C7H3F4NO2
- Molecular Weight:209.1
5470-18-8
447 suppliers
$6.00/5g
886510-09-4
100 suppliers
$167.00/250mg
Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: copper(l) iodide; 1,10-Phenanthroline / N,N-dimethyl-formamide / 3 h / 100 - 110 °C / Inert atmosphere; Large scale
2.1: tetrabutyl ammonium fluoride / dimethyl sulfoxide / 8 h / Reflux; Large scale
3.1: N-ethyl-N,N-diisopropylamine; n-butyllithium / tetrahydrofuran / 2 h / -80 - -70 °C / Inert atmosphere; Large scale
3.2: 0.5 h / -60 °C / Inert atmosphere; Large scale
References:
CN110627714,2019,A
876919-08-3
80 suppliers
$30.00/100mg
886510-09-4
100 suppliers
$167.00/250mg
393-53-3
198 suppliers
$10.00/1g
886510-09-4
100 suppliers
$167.00/250mg