3-Chloro-4-(3-fluorobenzyloxy)aniline synthesis
- Product Name:3-Chloro-4-(3-fluorobenzyloxy)aniline
- CAS Number:202197-26-0
- Molecular formula:C13H11ClFNO
- Molecular Weight:251.68
443882-99-3
180 suppliers
$6.00/1g
202197-26-0
303 suppliers
$6.00/1g
Yield:202197-26-0 100%
Reaction Conditions:
with H2;Pt/C in ethanol
Steps:
1.d (d)
(d) Preparation of 4-(3-fluorobenzyloxy)-3-chloro Aniline Under nitrogen, a Parr Shaker flask was charged with Pt/C 5% (135 mg) and ethanol (180 mL) and 4-(3-fluorobenzyloxy)-3-chloro nitrobenzene (13.5 g) was added. The reaction vessel was placed on a Parr Shaker Apparatus under 25 psi of H2 for 50 minutes. The catalyst was then removed by filtration through Celite and the filtrate concentrated to afford a light grey solid. The filtrate was triturated with diethyl ether and the solids collected by filtration (12.05 g, ~100% yield).
References:
Lackey, Karen Elizabeth;Spector, Neil;Wood lll, Edgar Raymond;Xia, Wenle US2004/53946, 2004, A1
3964-52-1
250 suppliers
$20.00/5g
456-41-7
291 suppliers
$13.00/25g
202197-26-0
303 suppliers
$6.00/1g
443882-99-3
180 suppliers
$6.00/1g
352-70-5
260 suppliers
$12.00/25mL
3964-52-1
250 suppliers
$20.00/5g
202197-26-0
303 suppliers
$6.00/1g
619-08-9
316 suppliers
$5.00/1g
202197-26-0
303 suppliers
$6.00/1g
456-41-7
291 suppliers
$13.00/25g
202197-26-0
303 suppliers
$6.00/1g