![426823-25-8](/CAS/GIF/426823-25-8.gif)
3-(4-TRIFLUOROMETHYL)PHENYLPYRIDINE synthesis
- Product Name:3-(4-TRIFLUOROMETHYL)PHENYLPYRIDINE
- CAS Number:426823-25-8
- Molecular formula:C12H8F3N
- Molecular Weight:223.19
![3-Chloropyridine](/CAS/GIF/626-60-8.gif)
626-60-8
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$13.00/5g
![4-Trifluoromethylphenylboronic acid](/CAS/GIF/128796-39-4.gif)
128796-39-4
430 suppliers
$10.00/5g
![3-(4-TRIFLUOROMETHYL)PHENYLPYRIDINE](/CAS/GIF/426823-25-8.gif)
426823-25-8
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Yield:426823-25-8 99%
Reaction Conditions:
Stage #1: 3-Chloropyridine;4-trifluoromethylphenylboronic acidwith palladium diacetate;(R)-6-dicyclohexylphoshino-6'-diphenylphosphino-3,3'-dimethoxy-2,2',4,4'-tetramethyl-1,1'-biphenyl in dodecane;butan-1-ol at 25; for 0.0833333 h;Glovebox;Inert atmosphere;Suzuki-Miyaura Coupling;
Stage #2: with cesiumhydroxide monohydrate in dodecane;water;butan-1-ol at 80; for 4 h;Glovebox;Inert atmosphere;Suzuki-Miyaura Coupling;
References:
Yang, Junfeng;Liu, Sijia;Zheng, Jian-Feng;Zhou, Jianrong [European Journal of Organic Chemistry,2012,# 31,p. 6248 - 6259,12] Location in patent:supporting information
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![4-Trifluoromethylphenylboronic acid](/CAS/GIF/128796-39-4.gif)
128796-39-4
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![3-(4-TRIFLUOROMETHYL)PHENYLPYRIDINE](/CAS/GIF/426823-25-8.gif)
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![3-Iodopyridine](/CAS/GIF/1120-90-7.gif)
1120-90-7
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![4-Trifluoromethylphenylboronic acid](/CAS/GIF/128796-39-4.gif)
128796-39-4
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$10.00/5g
![3-(4-TRIFLUOROMETHYL)PHENYLPYRIDINE](/CAS/GIF/426823-25-8.gif)
426823-25-8
11 suppliers
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