(2S,3S)-3-METHYLPYRROLIDINE-2-CARBOXYLIC ACID synthesis
- Product Name:(2S,3S)-3-METHYLPYRROLIDINE-2-CARBOXYLIC ACID
- CAS Number:10512-89-7
- Molecular formula:C6H11NO2
- Molecular Weight:129.16
1101927-73-4
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10512-89-7
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Yield:10512-89-7 90%
Reaction Conditions:
Stage #1: methyl (2S,3S)-N-tert-butoxycarbonyl-3-methylprolinatewith hydrogenchloride in water; for 3 h;Reflux;
Stage #2: with ammonium hydroxide;dowex 50Wx8 in water;
References:
Oba, Makoto;Saegusa, Tsuneki;Nishiyama, Naohiro;Nishiyama, Kozaburo [Tetrahedron,2009,vol. 65,# 1,p. 128 - 133] Location in patent:experimental part
73-32-5
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10512-89-7
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921-74-4
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138871-60-0
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817554-70-4
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10512-89-7
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