2-[4-[(2RS)-2-HYDROXY-3[(1-METHYLETHYL)AMINO]PROPOXY]PHENYL]ACETONITRILE synthesis
- Product Name:2-[4-[(2RS)-2-HYDROXY-3[(1-METHYLETHYL)AMINO]PROPOXY]PHENYL]ACETONITRILE
- CAS Number:29277-73-4
- Molecular formula:C14H20N2O2
- Molecular Weight:248.32
29122-68-7
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Yield:29277-73-4 96%
Reaction Conditions:
with (dimethoxy)methylsilane;copper diacetate;1,2-bis-(dicyclohexylphosphino)ethane in tetrahydrofuran at 20; for 12 h;Sealed tube;
References:
Liu, Richard Y.;Bae, Minwoo;Buchwald, Stephen L. [Journal of the American Chemical Society,2018,vol. 140,# 5,p. 1627 - 1631] Location in patent:supporting information
623-05-2
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29277-73-4
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14191-95-8
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29277-73-4
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