ChemicalBook CAS DataBase List PERFLUORO(2,5-DIMETHYL-3,6-DIOXANONANOIC) ACID METHYL ESTER

PERFLUORO(2,5-DIMETHYL-3,6-DIOXANONANOIC) ACID METHYL ESTER synthesis

2synthesis methods

Product Name:PERFLUORO(2,5-DIMETHYL-3,6-DIOXANONANOIC) ACID METHYL ESTER
CAS Number:26131-32-8
Molecular formula:C10H3F17O4
Molecular Weight:510.1

67-56-1 Synthesis

67-56-1
751 suppliers
$7.29/5ml-f

2,5-BIS(TRIFLUOROMETHYL)-3,6-DIOXAUNDECAFLUORONONANOYL FLUORIDE

2641-34-1
140 suppliers
$45.00/1 g

PERFLUORO(2,5-DIMETHYL-3,6-DIOXANONANOIC) ACID METHYL ESTER

26131-32-8
72 suppliers
$29.19/1g

Yield: 94%

Reaction Conditions:

with triethylamine at 0 - 20; for 6 h;

Steps:

Preparation of methyl perfluoroalkyl ether carboxylate
The methyl perfluoroalkyl ether carboxylate was prepared by esterfication of perfluorinated ether acid fluoride with methanol. A mixed solution of 41.11 g anhydrous triethylamine (0.40 mol) in 47.5 g anhydrous methanol (1.48 mol) was added dropwise into 185 g perfluoro-2,5-dimethyl-3,6-dioxa-nonanoic acid fluoride (0.37 mol) in a dry three-neck flask under agitation over a period of 2 h at 0 °C. The mixture was agitated for another 4 h and the temperature of reaction mass was maintained at room temperature. Subsequently, the reaction mixture was poured into a separating funnel. The fluorocarbon layer was washed with sodium bicarbonate solution and dried over anhydrous sodium sulfate to obtain the crude product. The crude product was distilled to give 178.43 g methyl perfluoro-2,5-dimethyl-3,6-dioxa-nonanoate (yield 94%) boiling at 145 °C at 760 mmHg. IR: 2969,1792, 1290, 1237, 1145, 1040, 994 cm^-1. ¹H-NMR (500 MHz, CDCl₃): δ 3.99 (3H, s, CH₃). ¹³C-NMR (125 MHz, CDCl₃): δ 54.60 (-CH₃-).

References:

Shi, Xiang;Shi, Hongxin;Wu, Hongke;Shen, HaiMin [Research on Chemical Intermediates,2018,vol. 44,# 9,p. 5091 - 5105]

1514-87-0 Synthesis