ChemicalBook CAS DataBase List 7-Hydroxy-2,3-dihydro-1H-cyclopenta[c]chromen-4-one

7-Hydroxy-2,3-dihydro-1H-cyclopenta[c]chromen-4-one synthesis

9synthesis methods

Product Name:7-Hydroxy-2,3-dihydro-1H-cyclopenta[c]chromen-4-one
CAS Number:21260-41-3
Molecular formula:C12H10O3
Molecular Weight:202.21

10472-24-9
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108-46-3 Synthesis

108-46-3
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7-Hydroxy-2,3-dihydro-1H-cyclopenta[c]chromen-4-one

21260-41-3
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$60.00/100mg

Yield: 57.4%

Reaction Conditions:

with bismuth(III) nitrate at 80; for 4 h;

Steps:

1.3
3) 7.1 g (50 mmol) of 2-oxocyclopentanecarboxy- late methyl ester, 5.5 g (50 mmol) of resorcinol and bismuth nitrate pentahydrate were heated to 80° C. and the reaction was carried out for 4 hours. Afier the reaction was completed, the reaction mixture was cooled to room temperature and the reaction liquid was poured into water and yellowish solid was precipitated. Stirring was performed for 30 mm and filtration leadto solid. Recrystallizationwith 95% ethanol gave 5.8 g of white solid. The yield was 5 7.4%.

References:

Zhang, Guisen;Chen, Yin;Xu, Xiangqing;Liu, Xin;Zhao, Song;Liu, Bifeng;Yu, Miquan;Qiu, Yinli US2014/171442, 2014, A1 Location in patent:Paragraph 0076