ChemicalBook CAS DataBase List 1-Phenyl-2-nitropropene

1-Phenyl-2-nitropropene synthesis

11synthesis methods

Product Name:1-Phenyl-2-nitropropene
CAS Number:705-60-2
Molecular formula:C9H9NO2
Molecular Weight:163.17

101-39-3
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$7.00/25g

705-60-2
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$10.00/1g

Yield:705-60-2 39%

Reaction Conditions:

with copper(II) nitrate trihydrate in water;acetonitrile at 130; for 12 h;

Steps:

15 Example-15

Add 0.3 mmol a-methylcinnamaldehyde, 0.45 ηηη1 tribasic copper nitrate to a 15 mL pressure tube, and then add 3 mL of a mixture of acetonitrile and water (V (acetonitrile): V (water) = 100:1) As a solvent. Next, stirring was performed at 130° (magnetic stirring for 12 hours). Then, two-passage silica gel column chromatography (100-200 mesh) was added to the reaction solution, and the solvent was removed by distillation under reduced pressure. The residue was separated by column chromatography. Using a mixture of V (petroleum ether):V (ethyl acetate) = 20:1 as eluent, the eluent containing the target product was collected, and the solvent was distilled off to obtain pure product. The amount of pure product was: 0.117 mmol The material was a yellow solid and the chemical name was 2-methyl-2-nitrostyrene in a yield of 39%.

References:

CN107641086,2018,A Location in patent:Paragraph 0082-0084