ChemicalBook CAS DataBase List 2-METHYLVINYLPHOSPHONIC ACID

2-METHYLVINYLPHOSPHONIC ACID synthesis

5synthesis methods

Product Name:2-METHYLVINYLPHOSPHONIC ACID
CAS Number:4721-36-2
Molecular formula:C3H7O3P
Molecular Weight:122.06

5035-79-0
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4721-36-2
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4167-10-6
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Yield:-

Reaction Conditions:

with sodium nitrite in water;Cooling with ice;

Steps:

General Procedure

General procedure: 1-aminoalkylphosphonic acid 1 (3.0 mmol, 1 eqiv) was added tocooled in water bath 0.67M solution of NaNO2 (6.0 mmol, 2 equiv, 9.0 mL). Solution orsuspension was stirred by the means of magnetic stirrer until the stoichiometric volumeof gas was evolved and additionally for 12 h. 1H and 31P NMR spectra were recorded afterthat time and additionally after few days. The composition of mixture was calculatedbased on the integration of signals on the 31P NMR spectra.

References:

Brol, Anna;Olszewski, Tomasz K. [Molecules,2022,vol. 27,# 24,art. no. 8849] Location in patent:supporting information