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ChemicalBook CAS DataBase List 2-(Methacryloyloxy)ethyl acetoacetate
21282-97-3

2-(Methacryloyloxy)ethyl acetoacetate synthesis

2synthesis methods
-

Yield:21282-97-3 84.6%

Reaction Conditions:

with aluminum oxide;2-methylbenzene-1,4-diol;potassium hydroxide at 122; for 1.5 h;Reagent/catalyst;Temperature;

Steps:

4 Example 4
Add raw hydroxyethyl methacrylate (HEMA) in a flask and ethyl acetoacetate 32.5g (AAA) 65g, was added with stirring KOH / Al2O3(Catalyst) and 0.5g methyl hydroquinone (polymerization inhibitor) 0.065 g, and heated to 122 deg.] C, side reactions take manner while distilling ethanol byproduct was distilled off under stirring stopped the reaction after stirring for 1.5 hours the reaction was cooled after filtering the reaction product of the catalyst and the liquid product was separated by distillation distilled liquid product thus Unreacted ethyl acetoacetate, 51.4g distilled liquid product resulting finished product is AAEM, sampling gas chromatography analysis determined an amount of 88.1% calculate product yield was 84.6%.

References:

Weifang Kemai Chemical Co., Ltd;Li, Qianqian;Song, Qi;Liu, Ying;Xing, Xiaohua;Yang, Hanhua CN105541611, 2016, A Location in patent:Paragraph 0018

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