ChemicalBook CAS DataBase List 2-(DODECYLOXY)ETHANOL

2-(DODECYLOXY)ETHANOL synthesis

10synthesis methods

Product Name:2-(DODECYLOXY)ETHANOL
CAS Number:4536-30-5
Molecular formula:C14H30O2
Molecular Weight:230.39

107-21-1 Synthesis

107-21-1
1334 suppliers
$10.00/25g

143-15-7 Synthesis

143-15-7
441 suppliers
$5.00/25g

4536-30-5
50 suppliers
$186.00/1ml

Yield:4536-30-5 69%

Reaction Conditions:

with tetrabutylammomium bromide;potassium hydroxide in 1,4-dioxane at 100 - 105;

Steps:

Ethylene glycol and diethylene glycol monoalkyl ethers 8a-e (general procedure).
General procedure: Dioxane (15 mL), alkyl halide (25 mmol), and tetrabutylammonium bromide (0.4 g, 1.2 mmol) were added to a solution of KOH (1.6 g, 27.5 mmol) in glycol (75-125 mmol). After stirring at 100-105 °C for 5-10 h, the reaction mixture was diluted with CHCl3 (15 mL) and water (10 mL). The organic layer was separated, washed with water (3×20 mL), dried with Na2SO4, and evaporated in vacuo, and the residue was distilled using Vigreux column. For each particular case, the ratio of the starting reagents, yields, physicochemical parameters, and 1H NMR spectral data for monoalkyl ethers 8a-e are givenin Table 6.

References:

Kharlamov;Artyushin;Bondarenko [Russian Chemical Bulletin,2014,vol. 63,# 11,p. 2445 - 2454][Izv. Akad. Nauk, Ser. Khim.,2014,# 11,p. 2445 - 2454]

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4292-19-7 Synthesis