ChemicalBook CAS DataBase List 2-Chloropropene

2-Chloropropene synthesis

6synthesis methods

Product Name:2-Chloropropene
CAS Number:557-98-2
Molecular formula:C3H5Cl
Molecular Weight:76.52

1,2-Propadiene adds hydrogen chloride to yield 2-chloropropene. One early synthesis involves dehydrohalogenation of 1,2-dichloropropane with potassium hydroxide.

5281-20-9 Synthesis

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557-98-2
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Yield:557-98-2 71%

Reaction Conditions:

Stage #1:acetone with magnesium sulfate;hydrazine hydrate at 20;
Stage #2:acetone hydrazone with N-chloro-succinimide in dichloromethane at -10 - 0;

Steps:

2.1 Example 2
A mixture of acetone (58 g, 1 mol), 75% hydrazine hydrate (200 g, 3 mol), anhydrous magnesium sulfate (360 g, 3 mol) andThe mixture was stirred at room temperature and the reaction was completed. The reaction mixture was filtered and the solid was washed with 30 mL of methanol. The solvent was evaporated to dryness and 1200 mL of dichloromethane and triethylamine (506 g, 5 mol) were added. The temperature was -10 ° C to 0 ° C, A solution of NCS (334 g, 2.5 [pi] o1) dissolved in 420 mL of dichloromethane was added. After the reaction was complete, 10% hydrochloric acid was added to adjust pH = 3-4. The organic layer was separated, 20 mL of sulfolane was added and 20-23 ° C of the distillate was distilled at atmospheric pressure to obtain 54.3 g of isopropenyl chloride as a colorless liquid. GC: 99.5%, yield 71%;

References:

Cangzhou Puri Oriental Technology Co., Ltd.;Leng, Yanguo;Liu, Jinzhou;Feng, Xuemin CN105503923, 2016, A Location in patent:Paragraph 0019

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67-64-1
6 suppliers
$17.30/10ml

557-98-2
75 suppliers
$45.00/5 g

References