ChemicalBook CAS DataBase List 2-CHLOROBENZANILIDE

2-CHLOROBENZANILIDE synthesis

12synthesis methods

Product Name:2-CHLOROBENZANILIDE
CAS Number:6833-13-2
Molecular formula:C13H10ClNO
Molecular Weight:231.68

609-65-4 Synthesis

609-65-4
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6833-13-2
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$50.00/250mg

Yield:6833-13-2 98%

Reaction Conditions:

with triethylamine hydrochloride;triethylamine in chloroform;water;benzene;

Steps:

I Preparation of 2-chlorobenzoyl anilide

EXAMPLE I Preparation of 2-chlorobenzoyl anilide Fourth and seven-tenths grams (4.7 g) (0.05 mole) anilide and 5.10 g triethylamine are mixed in 150 milliliters (ml) of benzene by stirring. A solution of 8.75 g (0.05 mole) 2-chlorobenzoyl chloride in 50 ml chloroform is added to the first mixture through a dropping funnel. An exothermic reaction takes place. After the addition is finished, the mixture is refluxed for 1/2 hour. The mixture is cooled with the product solidifying. The product is filtered, added to water, and stirred to dissolve triethylamine hydrochloride. The product is filtered again and dried to yield 11.3 g of the desired product (98% yield) m.p. 115°-117° C.

References:

US4390549,1983,A

609-65-4 Synthesis

609-65-4
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$21.00/25g

62-53-3 Synthesis