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ChemicalBook CAS DataBase List 2-Chloro-5-aminophenol
6358-06-1

2-Chloro-5-aminophenol synthesis

5synthesis methods
-

Yield:6358-06-1 98%

Reaction Conditions:

Pt/C in ethyl acetate

Steps:

1.b b).
b). 2-Chloro-5-aminophenol A solution of 2-chloro-5-nitrophenol (25 g, 0.14 mol) in ethyl acetate (150 mL) was treated with 5% Pt/C (250 mg) and the mixture shaken under a hydrogen atmosphere (30 psi) for 4 h. The mixture was filtered through Celiteg and the residue washed well with hot ethyl acetate. The filtrate was treated with activated charcoal and re-filtered as above. Evaporation of the ethyl acetate gave a solid (19.8 g, 98%).

References:

Dhanak, Dashyant;Knight, Steven David US2003/100580, 2003, A1

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