ChemicalBook CAS DataBase List 2-Bromodibenzofuran

2-Bromodibenzofuran synthesis

9synthesis methods

Product Name:2-Bromodibenzofuran
CAS Number:86-76-0
Molecular formula:C12H7BrO
Molecular Weight:247.09

2-Bromodibenzofuran is used as an intermediate in medicine, organic and materials. It can be prepared by the bromination of Dibenzofuran.

132-64-9 Synthesis

132-64-9
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86-76-0
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Yield:86-76-0 83%

Reaction Conditions:

with N-Bromosuccinimide;zirconium(IV) chloride in N,N-dimethyl-formamide at 70; for 18 h;Inert atmosphere;Schlenk technique;

Steps:

Dibenzofuran (3.36 g, 20 mmol), NBS (3.92 g, 22 mmol), zirconium chloride (0.10 g, 0.44 mmol), and DMF (40 mL) were placed in a 100 mL Schlenk flask equipped with a stirrer and purged with argon And the mixture was stirred at 70 ° C. for 18 hours. The reaction solution was added to water (200 mL) to precipitate a solid and stirred in suspension for 30 minutes.The suspension was filtered and hot water (100 mL) at 90 ° C. was poured slowly from above the solid on the filter paper. The solid on the filter paper was recovered and then dried to obtain 4.1 g of the desired product (yield: 83%).

References:

KANTO CHEMICAL COMPANY INCORPORATED;JAPAN BROADCASTING CORPORATION;FUKAGAWA, HIROHIKO;SHIMIZU, TAKAHISA;TAKAHASHI, JUNPEI;SHINNAI, TOSHINOBU;TSUCHIYA, KAZUHIKO JP2016/175849, 2016, A Location in patent:Paragraph 0144

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132-64-9 Synthesis

132-64-9
356 suppliers
$5.00/10g

86-76-0
222 suppliers
$6.00/1g