2-Acetyl-5-bromothiophene synthesis
- Product Name:2-Acetyl-5-bromothiophene
- CAS Number:5370-25-2
- Molecular formula:C6H5BrOS
- Molecular Weight:205.07
1003-09-4
481 suppliers
$10.00/25g
75-36-5
579 suppliers
$17.92/100G
5370-25-2
271 suppliers
$8.00/5g
Yield:5370-25-2 86.1%
Reaction Conditions:
in dichloromethane
Steps:
R.1 2-Acetyl-5-bromothiophene (b-1) STR41
REFERENTIAL EXAMPLE 1 2-Acetyl-5-bromothiophene (b-1) STR41 When 1.56 ml (1.1 equivalents) of acetyl chloride was added to a solution of 3.26 g (0.02 mmol) of 2-bromothiophene in 30 ml of CH2 Cl2, the mixture foamed and turned black. After stirring for 1 hr. at room temperature, the mixture was mixed with ice and concentrated hydrochloric acid. While being decolored with active carbon, the mixture was extracted with CH2 Cl2, whereby 3.53 g (Yield: 86.1%) of the objective product, 2-acetyl-5-bromothiophene (b-1) was obtained as colorless crystals.
References:
Shinogi & Co., Ltd. US4839365, 1989, A
88-15-3
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5370-25-2
271 suppliers
$8.00/5g
1003-09-4
481 suppliers
$10.00/25g
108-24-7
5 suppliers
$14.00/250ML
5370-25-2
271 suppliers
$8.00/5g
1003-09-4
481 suppliers
$10.00/25g
64-19-7
1563 suppliers
$10.00/25ML
5370-25-2
271 suppliers
$8.00/5g
