![5465-90-7](/CAS/GIF/5465-90-7.gif)
2-[(4-chlorophenyl)amino]acetic acid synthesis
- Product Name:2-[(4-chlorophenyl)amino]acetic acid
- CAS Number:5465-90-7
- Molecular formula:C8H8ClNO2
- Molecular Weight:185.61
![glycine, N-(4-chlorophenyl)-, ethyl ester](/CAS/GIF/2521-89-3.gif)
2521-89-3
33 suppliers
$41.00/1g
![2-[(4-chlorophenyl)amino]acetic acid](/CAS/GIF/5465-90-7.gif)
5465-90-7
32 suppliers
$44.00/250mg
Yield:5465-90-7 98%
Reaction Conditions:
Stage #1: N-(4-chlorophenyl)glycine ethyl esterwith lithium hydroxide monohydrate;lithium hydroxide monohydrate in tetrahydrofuran at 0 - 20;
Stage #2: with hydrogenchloride in tetrahydrofuran;lithium hydroxide monohydrate at 20; pH=3 - 4;
References:
Wu, Chunrui;Fang, Yuesi;Larock, Richard C.;Shi, Feng [Organic Letters,2010,vol. 12,# 10,p. 2234 - 2237] Location in patent:supporting information; experimental part
![4-Chloroaniline](/CAS/GIF/106-47-8.gif)
106-47-8
485 suppliers
$5.00/5G
![2-[(4-chlorophenyl)amino]acetic acid](/CAS/GIF/5465-90-7.gif)
5465-90-7
32 suppliers
$44.00/250mg
![4-Chloroaniline](/CAS/GIF/106-47-8.gif)
106-47-8
485 suppliers
$5.00/5G
![Glyoxylic acid](/CAS/GIF/298-12-4.gif)
298-12-4
455 suppliers
$5.00/25g
![2-[(4-chlorophenyl)amino]acetic acid](/CAS/GIF/5465-90-7.gif)
5465-90-7
32 suppliers
$44.00/250mg
![4-Chloroaniline](/CAS/GIF/106-47-8.gif)
106-47-8
485 suppliers
$5.00/5G
![Bromoacetyl bromide](/CAS/GIF/598-21-0.gif)
598-21-0
311 suppliers
$10.00/10g
![2-[(4-chlorophenyl)amino]acetic acid](/CAS/GIF/5465-90-7.gif)
5465-90-7
32 suppliers
$44.00/250mg