2,3-Dimethylpyridine-N-oxide synthesis
- Product Name:2,3-Dimethylpyridine-N-oxide
- CAS Number:22710-07-2
- Molecular formula:C7H9NO
- Molecular Weight:123.15
583-61-9
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$5.00/5g
22710-07-2
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$16.00/1g
Yield:22710-07-2 99.8%
Reaction Conditions:
with phosphotungstic acid;dihydrogen peroxide at 45 - 85; for 8 h;Reagent/catalyst;Temperature;
Steps:
8.1; 9.1; 10.1; 11.1; 12.1; 13.1; 14.1; 2.1
1. Add 2,3-dimethylpyridine 50 g (467 mmol) to a 1000 ml four-mouth bottle, add 2 g (0.35 mmol) of phosphotungstic acid, at 45 °C, slowly add 35% Hydrogen peroxide 49.9 g (514 mmol), control hydrogen peroxide addition time of 3 hours, add bi, heat up to 85 °C, incubated at 85 °C for 5 hours, and then cooled to 50 °C and then passed into the vacuum distillation bottle, the temperature of the controlled vacuum distillation bottle ≤ 85 °C, the inner pressure of the bottle is -0.1 ~ -0.08Mpa, decompression distillation to give 2,3-dimethylpyridine nitrogen oxide 57.4 g, purity of 96%, yield of 99.8%.
References:
CN113831281,2021,A Location in patent:Paragraph 0035; 0037; 0039; 0041; 0043; 0045; 0047; 0051
