ChemicalBook CAS DataBase List 2-(2-PYRIDYL)BENZIMIDAZOLE

2-(2-PYRIDYL)BENZIMIDAZOLE synthesis

15synthesis methods

Product Name:2-(2-PYRIDYL)BENZIMIDAZOLE
CAS Number:1137-68-4
Molecular formula:C12H9N3
Molecular Weight:195.22

1121-60-4
516 suppliers
$10.60/10gm:

95-54-5 Synthesis

95-54-5
517 suppliers
$9.00/1g

1137-68-4
162 suppliers
$14.00/1g

Yield:1137-68-4 99%

Reaction Conditions:

with Ag₂CO₃/celite in ethanol at 70; for 3 h;

Steps:

General procedure for the synthesis of 2-substitutedbenzimidazoles and benzothiazoles

General procedure: To a mixture of 1,2-phenylenediamines (1.0 mmol) andaldehydes (1.1 mmol) in ethanol, 25 mol % of Ag2CO3/Celite (3 mL) was added. The resulting mixture was stirredat 70 °C for 3 h. After this time, the reaction mixture wasdiluted with ethanol (50 mL) and the catalyst was separatedby filtration. Water was then added to the organic layer, andthe products were filtered and washed with water. All of theproducts are known compounds and characterized easily bycomparison with melting point, IR, [1-6] H NMR spectraldata reported in literature.

References:

Soleimani, Ebrahim;Khodaei, Mohammad Mehdi;Yazdani, Hossein;Saei, Parisa;Zavar Reza, Javad [Journal of the Iranian Chemical Society,2015,vol. 12,# 7,p. 1281 - 1285]

3731-51-9 Synthesis