ChemicalBook CAS DataBase List 2,2'-Bis(trifluoromethyl)benzidine

2,2'-Bis(trifluoromethyl)benzidine synthesis

9synthesis methods

Product Name:2,2'-Bis(trifluoromethyl)benzidine
CAS Number:341-58-2
Molecular formula:C14H10F6N2
Molecular Weight:320.23

2,2'-Bis(trifluoromethyl)benzidine is mainly used in microelectronics, optoelectronics field, used to prepare very low dielectric constant, very low surface free energy, high mechanical strength, high wear resistance, colorless transparent PI material, is the most well-known monomer containing fluorine PI diamine monomer.2,2'-Bis(trifluoromethyl)benzidine can be synthesized from 1,1'-Biphenyl, 4,4'-dinitro-2,2'-bis(trifluoromethyl).

1,1'-Biphenyl, 4,4'-dinitro-2,2'-bis(trifluoromethyl)

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Yield:341-58-2 98.8%

Reaction Conditions:

with Adams’s catalyst;hydrogen;palladium⁽⁰⁾;2-hydroxyethylamine in tetrahydrofuran at 55; under 2250.23 Torr; for 2 h;Temperature;Pressure;

Steps:

1-7 Example 3: (The catalyst was applied twice)

100g of 2,2'-bis(trifluoromethyl)-4,4'dinitrobiphenyl was added to the reaction kettle, 500g of solvent tetrahydrofuran was added, 0.1g of new catalyst was added, and 0.1g of co-catalyst 2-aminoethanol was added. g, apply the wet weight 5g of the catalyst recovered in Example 2, and tighten the reaction kettle. Fill with nitrogen to test for leaks, and after confirming that there is no leak point, turn on stirring to carry out nitrogen replacement and hydrogen replacement. When the temperature was raised to 55°C, the hydrogen pressure was 0.3 MPa, and the reaction was continued for 1 h. The pressure of the reaction kettle basically did not change, and the temperature was kept for 1 h. After the reaction is completed, hot filtration is carried out, and the filter cake is washed with the hot solvent tetrahydrofuran, put back into the reaction kettle, and applied in the next batch. The filtrate was stirred and slowly cooled to 5°C, and white crystals were obtained through crystallization, filtration and washing. The obtained white crystals were dried under reduced pressure to obtain 2,2'-bis(trifluoromethyl)-4,4'diaminobiphenyl. Detection content 99.84%,The molar yield reached 98.8%,

References:

CN114957015,2022,A Location in patent:Paragraph 0039-0055