3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YLBORONIC ACID synthesis
- Product Name:3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YLBORONIC ACID
- CAS Number:169126-64-1
- Molecular formula:C15H23BO2
- Molecular Weight:246.15
5419-55-6
386 suppliers
$12.00/5g
119999-22-3
82 suppliers
$22.00/1g
169126-64-1
65 suppliers
$73.00/250mg
Yield:169126-64-1 73%
Reaction Conditions:
Stage #1: 2-bromo-3-methyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalenewith n-butyllithium in tetrahydrofuran;hexane at -78; for 0.333333 h;Inert atmosphere;
Stage #2: Triisopropyl borate in tetrahydrofuran;hexane at -78; for 2 h;Inert atmosphere;
Stage #3: with hydrogenchloride;water in tetrahydrofuran;hexane at 20; for 1 h;
References:
Yamada, Shoya;Kawasaki, Mayu;Fujihara, Michiko;Watanabe, Masaki;Takamura, Yuta;Takioku, Maho;Nishioka, Hiromi;Takeuchi, Yasuo;Makishima, Makoto;Motoyama, Tomoharu;Ito, Sohei;Tokiwa, Hiroaki;Nakano, Shogo;Kakuta, Hiroki [Journal of Medicinal Chemistry,2019,vol. 62,# 19,p. 8809 - 8818]
119999-22-3
82 suppliers
$22.00/1g
169126-64-1
65 suppliers
$73.00/250mg
13780-71-7
3 suppliers
inquiry
121-43-7
369 suppliers
$15.00/25ml
119999-22-3
82 suppliers
$22.00/1g
169126-64-1
65 suppliers
$73.00/250mg
6683-48-3
150 suppliers
$8.00/1g
169126-64-1
65 suppliers
$73.00/250mg
110-03-2
354 suppliers
$6.00/25g
169126-64-1
65 suppliers
$73.00/250mg