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ChemicalBook CAS DataBase List 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE
109806-71-5

4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: thionyl chloride / toluene / 1 h / 85 - 90 °C / Large scale reaction
2.1: toluene / 3 h / 80 °C / Large scale reaction
2.2: pH 1 / Large scale reaction
3.1: water / toluene

References:

Reiter, Jozsef;Trinka, Peter;Bartha, Ferenc L.;Pongo, Laszlo;Volk, Balazs;Simig, Gyula [Organic Process Research and Development,2012,vol. 16,# 7,p. 1279 - 1282]

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