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ChemicalBook CAS DataBase List 1-Bromo-2,6-difluorobenzene
64248-56-2

1-Bromo-2,6-difluorobenzene synthesis

4synthesis methods
-

Yield:64248-56-2 98 %Spectr.

Reaction Conditions:

Stage #1: 2,6-difluorobenzoic acidwith (tri-tert-butylphosphane)gold(I) chloride;silver(l) oxide in N,N-dimethyl-formamide at 100; for 3 h;Inert atmosphere;
Stage #2: with N-Bromosuccinimide in N,N-dimethyl-formamide at 50; for 1 h;Inert atmosphere;

References:

Cornella, Josep;Rosillo-Lopez, Martin;Larrosa, Igor [Advanced Synthesis and Catalysis,2011,vol. 353,# 8,p. 1359 - 1366] Location in patent:supporting information; experimental part

133117-48-3 Synthesis
Benzene, 1,3-difluoro-2-(triMethylsilyl)-

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