ChemicalBook CAS DataBase List 1,3-Propanesultone

1,3-Propanesultone synthesis

11synthesis methods

Product Name:1,3-Propanesultone
CAS Number:1120-71-4
Molecular formula:C3H6O3S
Molecular Weight:122.14

1,3-propane sultone is produced commercially by dehydrating gamma-hydroxy-propanesulfonic acid, which is prepared from sodium hydroxypropanesulfonate. this sodium salt is prepared by addition of sodium bisulfite to allyl alcohol.?

15909-83-8
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$10.00/25g

1120-71-4
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$13.00/5g

Yield:1120-71-4 99.4%

Reaction Conditions:

Stage #1: 3-hydroxypropanesulfonic acidwith pyridinium p-toluenesulfonate at 55; for 2.5 h;Large scale;
Stage #2: with calcium oxide for 2 h;Reflux;Large scale;Temperature;

Steps:

6.2 Example 6
(2) Preparation of 1,3-propanesultone

Example 6
(2) Preparation of 1,3-propanesultone
To 110kg 3-hydroxy-1-propanesulfonic acid was added 1.5kg of pyridinium p-toluenesulfonate and 3kg zeolite. Dehydration reaction was done at 55°C for 2.5 hours. The reaction was subjected to distillation and the fraction 147-149°C was taken. 1kg of calcium oxide was added and was heated at reflux for 2 hours to give 95.5kg 1,3-propanesultone with a total yield of 99.4% and a purity of 99.99% or more containing less than 0.02%.

References:

CN105348254,2016,A Location in patent:Paragraph 0039; 0040; 0042