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ChemicalBook CAS DataBase List 1,1,1-TRIFLUORO-6-METHYLHEPTANE-2,4-DIONE
461-92-7

1,1,1-TRIFLUORO-6-METHYLHEPTANE-2,4-DIONE synthesis

2synthesis methods
-

Yield:461-92-7 19.5%

Reaction Conditions:

Stage #1: trifluoroacetic acid-methyl esterwith sodium hydride in tetrahydrofuran;Inert atmosphere;
Stage #2: 4-methyl-2-pentanone in tetrahydrofuran;Inert atmosphere;

References:

Simunek, Petr;Svobodova, Marketa;Machacek, Vladimir [Journal of Heterocyclic Chemistry,2009,vol. 46,# 4,p. 650 - 655] Location in patent:experimental part

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