Valspodar
|
- $29 - $2200
- Product name: Valspodar
- CAS: 121584-18-7
- MF: C63H111N11O12
- MW: 1214.62
- EINECS:1312995-182-4
- MDL Number:MFCD00907207
- Synonyms:Valspodar;3'-Keto-bmt(1)-Val(2)-cyclosporin a;Cyclosporin A, 6-((R-(E))-6,7-didehydro-N,4-dimethyl-3-oxo-L-2-aminooctanoic acid)-7-L-valine-;Sdz psc 833;Sdz-psc-833;Cyclo[[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoyl]-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl];6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoicacid]-7-L-valine-cyclosporinA;Valspodar(PSC-833,AMdray)
23 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 500μg
- 2mg
- 1mg
- 1
- 5mg
- 10mg
- 25mg
- 100mg
- 250mg
- 5 mg
- 10 mg
- ManufacturerAK Scientific
- Product numberX5944
- Product descriptionValspodar
- Packaging5mg
- Price$320
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3905
- Product descriptionValspodar
- Packaging5mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3905
- Product descriptionValspodar
- Packaging10mg
- Price$239
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFV28665
- Product descriptionValspodar
- Packaging25mg
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number20391
- Product descriptionPSC 833 ≥95%
- Packaging5 mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20391
- Product descriptionPSC 833 ≥95%
- Packaging10 mg
- Price$337
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20391
- Product descriptionPSC 833 ≥95%
- Packaging1mg
- Price$55
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20391
- Product descriptionPSC 833 ≥95%
- Packaging500μg
- Price$29
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-1074
- Product descriptionValspodar 99.27%
- Packaging1mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1074
- Product descriptionValspodar 99.27%
- Packaging5mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1074
- Product descriptionValspodar 99.27%
- Packaging10mg
- Price$920
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004250
- Product descriptionValspodar 98+%
- Packaging10mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004250
- Product descriptionValspodar 98+%
- Packaging5mg
- Price$98
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN12182
- Product descriptionValspodar
- Packaging5mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9813
- Product descriptionValspodar(PSC833) >98%
- Packaging100mg
- Price$1100
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9813
- Product descriptionValspodar(PSC833) >98%
- Packaging250mg
- Price$2200
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X5944 | Valspodar | 5mg | $320 | 2021-12-16 | Buy |
| ApexBio Technology | A3905 | Valspodar | 5mg | $133 | 2021-12-16 | Buy |
| ApexBio Technology | A3905 | Valspodar | 10mg | $239 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FV28665 | Valspodar | 25mg | $750 | 2021-12-16 | Buy |
| Cayman Chemical | 20391 | PSC 833 ≥95% | 5 mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 20391 | PSC 833 ≥95% | 10 mg | $337 | 2024-03-01 | Buy |
| Cayman Chemical | 20391 | PSC 833 ≥95% | 1mg | $55 | 2024-03-01 | Buy |
| Cayman Chemical | 20391 | PSC 833 ≥95% | 500μg | $29 | 2024-03-01 | Buy |
| ChemScene | CS-1074 | Valspodar 99.27% | 1mg | $200 | 2021-12-16 | Buy |
| ChemScene | CS-1074 | Valspodar 99.27% | 5mg | $550 | 2021-12-16 | Buy |
| ChemScene | CS-1074 | Valspodar 99.27% | 10mg | $920 | 2021-12-16 | Buy |
| Crysdot | CD31004250 | Valspodar 98+% | 10mg | $175 | 2021-12-16 | Buy |
| Crysdot | CD31004250 | Valspodar 98+% | 5mg | $98 | 2021-12-16 | Buy |
| CSNpharm | CSN12182 | Valspodar | 5mg | $130 | 2021-12-16 | Buy |
| DC Chemicals | DC9813 | Valspodar(PSC833) >98% | 100mg | $1100 | 2021-12-16 | Buy |
| DC Chemicals | DC9813 | Valspodar(PSC833) >98% | 250mg | $2200 | 2021-12-16 | Buy |
Properties
Melting point :143-145°C
alpha :D20 -255.1° (c = 0.5 in CHCl3)
Boiling point :1290.1±65.0 °C(Predicted)
Density :1.015±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :12.45±0.70(Predicted)
form :powder
color :white to beige
InChIKey :YJDYDFNKCBANTM-QCWCSKBGSA-N
alpha :D20 -255.1° (c = 0.5 in CHCl3)
Boiling point :1290.1±65.0 °C(Predicted)
Density :1.015±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :12.45±0.70(Predicted)
form :powder
color :white to beige
InChIKey :YJDYDFNKCBANTM-QCWCSKBGSA-N
Safety Information
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Description
PSC 833 is a non-immunosuppressant derivative of cyclosporine and potent multidrug-resistance (MDR) modulator. It restores sensitivity of MDR-P388 murine leukemia cells to cytostatic agents when used at concentrations of 70, 33, 45, 34, and 26 nM in combination with colchicine, vincristine , daunorubicin , doxorubicin , and etoposide , respectively. PSC 833 inhibits basal-to-apical transport and increases apical-to-basal transport of [14C]docetaxel in LLC-GA5-COLO150 cells that overexpress human P-glycoprotein (P-gp). In vivo, PSC 833 increases survival time in MDR-P388 tumor-bearing mice and in an MDR-L1210 leukemia mouse xenograft model when administered in combination with doxorubicin. PSC 833 also prolongs the anti-hyperalgesic effects of intraperitoneally administered pregabalin in a mouse model of cold stress-induced central pain.More related product prices
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