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ChemicalBook >> CAS DataBase List >> Topiroxostat

Topiroxostat

Topiroxostat price.
  • $50 - $801
  • Product name: Topiroxostat
  • CAS: 577778-58-6
  • MF: C13H8N6
  • MW: 248.24
  • EINECS:1592732-453-0
  • MDL Number:MFCD17167057
  • Synonyms:Topiroxostat;Topiroxostat,FYX-051;5-(2-Cyano-4-pyridyl)-3-(4-pyridyl)-1,2,4-triazole;Topiroxostat 5-(2-Cyano-4-pyridyl)-3-(4-pyridyl)-1,2,4-triazole;4-[5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile;2-Pyridinecarbonitrile, 4-[5-(4-pyridinyl)-1H-1,2,4-triazol-3-yl]-;Topiroxostat impurty;Topiroxostat C13H8N6 high quality Cas number:577778-58-6
18 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • Labseeker
  • Matrix Scientific
  • TRC
Package
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 5g
  • 25g
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number8836CN
  • Product descriptionTopiroxostat
  • Packaging5g
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001478
  • Product descriptionFYX-051 95.00%
  • Packaging5MG
  • Price$501.05
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1192
  • Product descriptionTopiroxostat
  • Packaging10mM(in 1mL DMSO)
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon3178
  • Product descriptionTopiroxostat 99%
  • Packaging50mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21267
  • Product descriptionTopiroxostat ≥98%
  • Packaging5mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21267
  • Product descriptionTopiroxostat ≥98%
  • Packaging10mg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21267
  • Product descriptionTopiroxostat ≥98%
  • Packaging50mg
  • Price$535
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21267
  • Product descriptionTopiroxostat ≥98%
  • Packaging100mg
  • Price$801
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM171330
  • Product description5-(2-Cyano-4-pyridyl)-3-(4-pyridyl)-1,2,4-triazole 98%
  • Packaging100mg
  • Price$619
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2033
  • Product descriptionTopiroxostat 99.68%
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2033
  • Product descriptionTopiroxostat 99.68%
  • Packaging25mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2033
  • Product descriptionTopiroxostat 99.68%
  • Packaging50mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2033
  • Product descriptionTopiroxostat 99.68%
  • Packaging100mg
  • Price$205
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001419
  • Product descriptionTopiroxostat 98+%
  • Packaging100mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001419
  • Product descriptionTopiroxostat 98+%
  • Packaging250mg
  • Price$425
  • Updated2021-12-16
  • Buy
  • ManufacturerLabseeker
  • Product numberSC-91234
  • Product descriptionTopiroxostat/FYX051 99.5
  • Packaging25g
  • Price$462
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8836CN Topiroxostat 5g $390 2021-12-16 Buy
American Custom Chemicals Corporation INB0001478 FYX-051 95.00% 5MG $501.05 2021-12-16 Buy
ApexBio Technology B1192 Topiroxostat 10mM(in 1mL DMSO) $77 2021-12-16 Buy
Axon Medchem Axon3178 Topiroxostat 99% 50mg $110 2021-12-16 Buy
Cayman Chemical 21267 Topiroxostat ≥98% 5mg $68 2024-03-01 Buy
Cayman Chemical 21267 Topiroxostat ≥98% 10mg $121 2024-03-01 Buy
Cayman Chemical 21267 Topiroxostat ≥98% 50mg $535 2024-03-01 Buy
Cayman Chemical 21267 Topiroxostat ≥98% 100mg $801 2024-03-01 Buy
Chemenu CM171330 5-(2-Cyano-4-pyridyl)-3-(4-pyridyl)-1,2,4-triazole 98% 100mg $619 2021-12-16 Buy
ChemScene CS-2033 Topiroxostat 99.68% 10mg $50 2021-12-16 Buy
ChemScene CS-2033 Topiroxostat 99.68% 25mg $75 2021-12-16 Buy
ChemScene CS-2033 Topiroxostat 99.68% 50mg $125 2021-12-16 Buy
ChemScene CS-2033 Topiroxostat 99.68% 100mg $205 2021-12-16 Buy
Crysdot CD31001419 Topiroxostat 98+% 100mg $240 2021-12-16 Buy
Crysdot CD31001419 Topiroxostat 98+% 250mg $425 2021-12-16 Buy
Labseeker SC-91234 Topiroxostat/FYX051 99.5 25g $462 2021-12-16 Buy

Properties

Boiling point :594.7±60.0 °C(Predicted)
Density :1.45±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 23.5 mg/mL (94.67 mM; Need ultrasonic and warming)
form :Powder
pka :7.47±0.10(Predicted)
color :White to off-white
InChI :InChI=1S/C13H8N6/c14-8-11-7-10(3-6-16-11)13-17-12(18-19-13)9-1-4-15-5-2-9/h1-7H,(H,17,18,19)
InChIKey :UBVZQGOVTLIHLH-UHFFFAOYSA-N
SMILES :C1(C#N)=NC=CC(C2NN=C(C3C=CN=CC=3)N=2)=C1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Topiroxostat is an orally-administered, non-purine, selective xanthine oxidase (XO) inhibitor developed for the treatment of hyperuricemia specifically for patients with gout in Japan. The drug was discovered and developed by Fuji Yakuhin. In contrast to conventional XO inhibitors such as febuxostat, topiroxostat interacts with key amino acid residues of the solvent channel.

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