Topiroxostat

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3178

CAS [577778-58-6]

MF C13H8N6
MW 248.24

Purity: 99%
Soluble in DMSO

Topiroxostat

Description

Topiroxostat is a potent xanthine oxidoreductase (XOR) inhibitor with xanthine as a substrate. In the absence of xanthine, however, FYX-051 itself is very slowly hydroxylated by the enzyme.

K Okamoto et al. The crystal structure of xanthine oxidoreductase during catalysis: Implications for reaction mechanism and enzyme inhibition. Proc Natl Acad Sci U S A 2004 May 25;101(21):7931-6.

T Nakamura et al. Effects of topiroxostat and febuxostat on urinary albumin excretion and plasma xanthine oxidoreductase activity in db/db mice. Eur J Pharmacol. 2016 Jun 5;780:224-31.

T Sato et al. Discovery of 3-(2-cyano-4-pyridyl)-5-(4-pyridyl)-1,2,4-triazole, FYX-051 - a xanthine oxidoreductase inhibitor for the treatment of hyperuricemia [corrected]. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6225-9.

Miscellaneous Xanthine Oxidase EC 1.17.3.2

Potent xanthine oxidoreductase (XOR) inhibitor

Chemical name

4-(5-(Pyridin-4-yl)-1H-1,2,4-triazol-3-yl)picolinonitrile

Parent CAS No.

[577778-58-6]

Order

Size	Unit Price	Stock
10 mg	$55.00	In Stock
50 mg	$110.00	In Stock

Need more? Bulk Inquiry

Related Products

Axon ID	Name	Description	From price
1174	Niraxostat	Xanthine oxidase inhibitor		$143.00
1175	TEI 6720	Xanthine oxidase inhibitor		$99.00

成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Customer Support

Customer Services

About Axon Medchem

Contact Us

Topiroxostat

Description

Chemical name

Parent CAS No.

Customer Support

About Axon Medchem

Download Product Catalog

Follow Us

成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Customer Support

Customer Services

About Axon Medchem

Contact Us

Topiroxostat

Description

Chemical name

Parent CAS No.

Related Products

Customer Support

About Axon Medchem

Download Product Catalog

Follow Us

Send us a message

Contact Us