Tie2 kinase inhibitor
16 prices
-
AK Scientific
-
Ambeed
-
ApexBio Technology
-
Cayman Chemical
-
Chemenu
-
Crysdot
-
CSNpharm
-
TRC
- 500μg
- 1mg
- 5mg
- 10mg
- 50mg
- 100mg
- 250mg
| Manufacturer |
Product number |
Product description |
Packaging |
Price |
Updated |
Buy |
|
AK Scientific
| 2758AH |
Tie2KinaseInhibitor |
250mg |
$1125 |
2021-12-16 |
Buy |
|
Ambeed
| A253059 |
Tie2kinase-IN-1 98+% |
10mg |
$101 |
2021-12-16 |
Buy |
|
Ambeed
| A253059 |
Tie2kinase-IN-1 98+% |
50mg |
$256 |
2021-12-16 |
Buy |
|
Ambeed
| A253059 |
Tie2kinase-IN-1 98+% |
100mg |
$384 |
2021-12-16 |
Buy |
|
ApexBio Technology
| A5979 |
Tie2kinaseinhibitor |
5mg |
$100 |
2021-12-16 |
Buy |
|
Cayman Chemical
| 17858 |
Tie2 Kinase Inhibitor ≥95% |
500μg |
$40 |
2024-03-01 |
Buy |
|
Cayman Chemical
| 17858 |
Tie2 Kinase Inhibitor ≥95% |
1mg |
$64 |
2024-03-01 |
Buy |
|
Cayman Chemical
| 17858 |
Tie2 Kinase Inhibitor ≥95% |
5mg |
$195 |
2024-03-01 |
Buy |
|
Cayman Chemical
| 17858 |
Tie2 Kinase Inhibitor ≥95% |
10mg |
$351 |
2024-03-01 |
Buy |
|
Chemenu
| CM330047 |
Tie2kinaseinhibitor1 95%+ |
100mg |
$819 |
2021-12-16 |
Buy |
|
Crysdot
| CD11005643 |
Tie2KinaseInhibitor 95+% |
10mg |
$112 |
2021-12-16 |
Buy |
|
Crysdot
| CD11005643 |
Tie2KinaseInhibitor 95+% |
50mg |
$315 |
2021-12-16 |
Buy |
|
Crysdot
| CD11005643 |
Tie2KinaseInhibitor 95+% |
100mg |
$525 |
2021-12-16 |
Buy |
|
CSNpharm
| CSN16555 |
Tie2kinase-IN-1 |
10mg |
$112 |
2021-12-16 |
Buy |
|
CSNpharm
| CSN16555 |
Tie2kinase-IN-1 |
100mg |
$525 |
2021-12-16 |
Buy |
|
TRC
| M264745 |
4-(6-Methoxy-2-naphthyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole |
10mg |
$295 |
2021-12-16 |
Buy |
Properties
Boiling point :699.8±55.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :≥22 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :Powder
pka :9.53±0.10(Predicted)
color :Light yellow to yellow
Safety Information
| Symbol(GHS): |
|
| Signal word: |
Warning |
| Hazard statements: |
| Code |
Hazard statements |
Hazard class |
Category |
Signal word |
Pictogram |
P-Codes |
| H302 |
Harmful if swallowed |
Acute toxicity,oral |
Category 4 |
Warning |
|
P264, P270, P301+P312, P330, P501 |
|
| Precautionary statements: |
| P264 |
Wash hands thoroughly after handling. |
| P264 |
Wash skin thouroughly after handling. |
| P270 |
Do not eat, drink or smoke when using this product. |
| P301+P312 |
IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
| P330 |
Rinse mouth. |
| P501 |
Dispose of contents/container to..… |
|
Description
Tunica interna endothelial cell kinase 2 (Tie2, also known as angiopoietin-1 receptor or tek) is an endothelium-specific receptor tyrosine kinase important for the development of embryonic vasculature and for angiogenesis and vascular maintenance in adult tissues. Tie2 kinase inhibitor reversibly and selectively blocks Tie2 kinase activity with an IC50 value of 250 nM. It is 200-fold more potent for inhibition of Tie2 compared to p38. Tie2 kinase inhibitor has been shown to reduce angiogenesis in a Matrigel neovascularization assay and to delay tumor growth in MOPC-315 plasmacytoma and SVR angiosarcoma xenograft models.