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ChemicalBook >> CAS DataBase List >> Silybin

Silybin

Silybin price.
  • $5 - $1159.39
  • Product name: Silybin
  • CAS: 22888-70-6
  • MF: C25H22O10
  • MW: 482.44
  • EINECS:245-302-5
  • MDL Number:MFCD00872186
  • Synonyms:Silybin-A ,98%;Silybin (50 mg);Silybin, 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin;Silybin，Silymarin;(2R)-2α-[[(2R,3R)-2,3-Dihydro-3β-(4-hydroxy-3-methoxyphenyl)-2α-(hydroxymethyl)-1,4-benzodioxin]-6-yl]-2,3-dihydro-3β,5,7-trihydroxy-4H-1-benzopyran-4-one;(2R,3R)-2-[[(2R,3R)-2,3-Dihydro-3β-(4-hydroxy-3-methoxyphenyl)-2α-(hydroxymethyl)-1,4-benzodioxin]-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one;Flavobion;silliver
41 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AHH
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • JR MediChem
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
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  • 10mg
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  • 25mg
  • 50mg
  • 100mg
  • 500mg
  • 10mM(in 1mL DMSO)
  • 1000mg
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  • 10000mg
  • 10g
  • 25g
  • 50000mg
  • 50g
  • 500g
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-S0276-G010
  • Product descriptionSilibinin ≥98%(HPLC)
  • Packaging10g
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1488
  • Product descriptionSilybin 98%
  • Packaging500g
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA177518
  • Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
  • Packaging25mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA177518
  • Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
  • Packaging100mg
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA177518
  • Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
  • Packaging1g
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA177518
  • Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
  • Packaging5g
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA177518
  • Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
  • Packaging10g
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA177518
  • Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
  • Packaging25g
  • Price$275
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0026191
  • Product descriptionSILYBIN 95.00%
  • Packaging1G
  • Price$614.87
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0026191
  • Product descriptionSILYBIN 95.00%
  • Packaging5G
  • Price$827.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0026191
  • Product descriptionSILYBIN 95.00%
  • Packaging10G
  • Price$1159.39
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1711
  • Product descriptionSilymarin
  • Packaging100mg
  • Price$47
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1711
  • Product descriptionSilymarin
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1711
  • Product descriptionSilymarin
  • Packaging500mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN99542
  • Product descriptionSilymarin ≥98%
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN95149
  • Product descriptionSilybinA ≥98%
  • Packaging10mg
  • Price$318
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-S0276-G010 Silibinin ≥98%(HPLC) 10g $65 2021-12-16 Buy
AHH API-1488 Silybin 98% 500g $700 2021-12-16 Buy
Ambeed A177518 (2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98% 25mg $5 2021-12-16 Buy
Ambeed A177518 (2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98% 100mg $6 2021-12-16 Buy
Ambeed A177518 (2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98% 1g $12 2021-12-16 Buy
Ambeed A177518 (2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98% 5g $66 2021-12-16 Buy
Ambeed A177518 (2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98% 10g $76 2021-12-16 Buy
Ambeed A177518 (2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98% 25g $275 2021-12-16 Buy
American Custom Chemicals Corporation API0026191 SILYBIN 95.00% 1G $614.87 2021-12-16 Buy
American Custom Chemicals Corporation API0026191 SILYBIN 95.00% 5G $827.1 2021-12-16 Buy
American Custom Chemicals Corporation API0026191 SILYBIN 95.00% 10G $1159.39 2021-12-16 Buy
ApexBio Technology N1711 Silymarin 100mg $47 2021-12-16 Buy
ApexBio Technology N1711 Silymarin 10mM(in 1mL DMSO) $60 2021-12-16 Buy
ApexBio Technology N1711 Silymarin 500mg $119 2021-12-16 Buy
Arctom CFN99542 Silymarin ≥98% 20mg $30 2021-12-16 Buy
Arctom CFN95149 SilybinA ≥98% 10mg $318 2021-12-16 Buy

Properties

Melting point :164-174°C
Boiling point :793.0±60.0 °C(Predicted)
alpha :D20 +11° (c = 0.25 in acetone + alcohol)
Density :1.527±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Acetone (Sparingly), DMSO, Methano (Sparingly)
form :Solid
pka :pKa 6.42±0.04 (Uncertain)
color :Pale Yellow
Water Solubility :54mg/L(24.99 ºC)
Merck :13,8607
Stability :Stable. Incompatible with strong oxidizing agents, strong bases.
LogP :4.232 (est)
CAS DataBase Reference :22888-70-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Silybin is an inhibitor of a wide variety of proteins, many of which are heavily involved in xenobiotic efflux and metabolism. Silybin is an inhibitor of P-glycoprotein-mediated cellular efflux and also inhibits xenobiotic oxidation by the CYP (cytochrome P450) superfamily of enzymes. This helps to contribute the apoptotic activity of this compound, which has been shown to be effective against a wide variety of cancer cell lines. Silybin is an inhibitor of 5-LO.

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