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ChemicalBook >> CAS DataBase List >> SPARSOMYCIN

SPARSOMYCIN

SPARSOMYCIN price.
  • $189 - $755
  • Product name: SPARSOMYCIN
  • CAS: 1404-64-4
  • MF: C13H19N3O5S2
  • MW: 361.44
  • EINECS:
  • MDL Number:MFCD01684112
  • Synonyms:Aids-012106;B 120121L19;nsc59729 ;sparsomycin ;Sparsomycin from Streptomyces sparsogenes;(E)-N-[(S)-1-(Hydroxymethyl)-2-[[(methylthio)methyl]sulfinyl]ethyl]-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxopyrimidine-5-yl)propenamide;U-19183;2-Propenamide, N-[(1S)-1-(hydroxymethyl)-2-[(R)-[(methylthio)methyl]sulfinyl]ethyl]-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidinyl)-, (2E)-
3 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
Package
  • 1mg
  • 5MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0015533
  • Product descriptionSPARSOMYCIN 95.00%
  • Packaging5MG
  • Price$500.41
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29934
  • Product descriptionSparsomycin
  • Packaging1mg
  • Price$189
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29934
  • Product descriptionSparsomycin
  • Packaging5mg
  • Price$755
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0015533 SPARSOMYCIN 95.00% 5MG $500.41 2021-12-16 Buy
Cayman Chemical 29934 Sparsomycin 1mg $189 2024-03-01 Buy
Cayman Chemical 29934 Sparsomycin 5mg $755 2024-03-01 Buy

Properties

Melting point :208-209° (dec)
alpha :D25 +69° (c = 0.5 in water)
Density :1.3893 (rough estimate)
refractive index :1.6390 (estimate)
storage temp. :2-8°C
solubility :DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
form :A solid
pka :8.67 in water, 9.05 in 40% ethanol
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Sparsomycin is a bacterial metabolite and a nucleoside analog of uracil that has been found in S. sparsogenes and has diverse biological activities. It is active against KB carcinoma cells, Gram-positive and Gram-negative bacteria, and fungi. Sparsomycin is an inhibitor of peptidyl transferase that interferes with tRNA binding to the A-site of the peptidyl transfer center and increases the binding of peptidyl-tRNA to the P-site. It inhibits protein synthesis in bacteria, archaea, and eukaryotes. Sparsomycin reduces tumor growth in a P388 mouse leukemia model and in a Walker 256 carcinosarcoma rat model.

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